Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin

Dormant glioblastoma cells acquire stem cell characteristics and are differentially affected by Temozolomide and AT101 treatment

Cellular dormancy is defined as a state in which cells enter quiescence driven by intrinsic or extrinsic factors, and striking parallels exist between the concept of cellular dormancy in malignancies and the cancer stem cell theory. We showed now that the proven dormancy markers insulin-like growth factor-binding protein 5, ephrin receptor A5 and histone cluster 1 H2B family member K were expre...

I-30: The Mesenchymal Stem Cell - The Origin of Endometriosis

What are the origin and route of diseases in Iran?

Since the gens change due to the environmental and individual factors, the role of these factors is now more important for the human health. In countries that the facilities such as clean air, healthy water and food, sport and recreational sites, social security and disease prevention programs readily available for all, the society is healthy and happy. Thus, the overall morbidities and mortali...

Stabilisation of the spine affected by malignancy.

A technique for securely stabilising the spine affected by malignancy has been developed. It provides excellent pain relief and some improvement of neurological deficit, and allows of laminectomy and radiotherapy. Although the technique is relatively simple, and the materials used are commonplace and inexpensive, it needs to be learnt which may mean that surgery for spinal malignancy will need ...

Rare thymic malignancy of B-cell origin - T-cell÷histiocyte-rich large B-cell lymphoma.

AIM T-cell÷histiocyte-rich B-cell lymphoma is a rare type of diffuse large B-cell lymphoma reported as involving primarily the thymus only by one paper in the English literature. CASE PRESENTATION A four and a half years old boy was admitted, after a sudden onset in the middle of the night, with superior vena cava syndrome, resuscitated cardiac and respiratory arrest and severe coma with Glas...